1. Urinary infection
  2. Enlarged Prostate in older men 
  3. Kidney or bladder stones 
  4. Period in women 
  5. Prostate infection 
  6. Kidney disease 
  7. Kidney trauma 
  8. Bladder cancer (mostly in smokers) 
  9. Kidney cancer 
  10. Blood thinning drugs (aspirin, coumadin/warfarin)
  11. Anti-swelling drugs (joint swelling and pain pills)
  12. Tough workout 

When blood is found in the urine, health care providers want to make sure there is not a serious health issue involved such as a tumor in the kidney or bladder. Urological cancers are rarely the cause of blood in the urine. Only about 2 or 3 of every 100 people with microscopic hematuria are found to have cancer.

When you actually see blood in the urine, it is called "gross hematuria." This is much more likely to be tied to a cancer or other health issue that needs medical care.

  • Men with known breast cancer or known or suspected prostate cancer should not take testosterone.
  • Men taking testosterone have a higher risk of getting urinary symptoms (such as urinating more often, blood in the urine, and enlarged prostate). In men who already have these problems, they could get worse. 
  • Men with kidney, liver, or heart problems may have a higher risk of water retention (edema). 
  • Testosterone replacement may make sleep apnea worse. 
  • If you are trying to father a child, you should not be on TRT. TRT can decrease your sperm count and fertility. Taking testosterone for a long time may harm fertility. 

  • Skin gels can cause rashes or skin reactions.
  • Some men experience tenderness in the breast, or enlarged breasts. 
  • Some men experience dizziness, lightheadedness, or feeling faint.
  • Some men become more emotionally sensitive, with mood swings.
  • Testosterone creams can impact women and children in close contact, especially pregnant women. Women and children should not touch unwashed clothes after treatment. 

So far, studies have found no increase in prostate cancer risk among men who take testosterone compared to men who don’t. This issue needs further research.

There are major concerns that taking testosterone can raise the risk of heart problems. These can include blood clots, heart attack and stroke. Two recent studies have suggested that TRT raises the risk of heart attack in men. The U.S. Federal Drug Administration is studying the risk of heart attack, stroke and death in men taking TRT.

There are also conflicting studies that suggest TRT may lower heart risk. More studies need to be done to be certain whether and how TRT changes men’s risk of heart attack. It’s important to ask your doctor about your heart health before you begin therapy.

Symptoms of low testosterone will remain. You may find other ways to increase your energy level or you may choose to live with changes in your sexual desire and body.

Erectile dysfunction (ED) is not the same as hypogonadism. It has other causes and requires other treatments. It’s important to talk about ED with your doctor as a separate issue. If you have normal testosterone levels, using TRT will not help your erection problems.

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